5.89286 % | BlackRock Institutional Trust Company, N.A. | 5,734,935 | 320,109 | 31.12.2023 |
5.44271 % | Rosenthal (Armon) | 5,296,841 | -18,837 | 4.3.2024 |
4.48978 % | The Vanguard Group, Inc. | 4,369,452 | -1,134,367 | 31.12.2023 |
4.16826 % | EcoR1 Capital, LLC | 4,056,548 | 0 | 31.12.2023 |
3.41585 % | Braidwell LP | 3,324,308 | -749,812 | 31.12.2023 |
3.30391 % | Morgan Stanley & Co. LLC | 3,215,364 | 918,410 | 31.12.2023 |
3.20338 % | State Street Global Advisors (US) | 3,117,529 | 280,822 | 31.12.2023 |
2.70742 % | Gerngross (Tillman U.) | 2,634,860 | 26,250 | 14.6.2023 |
2.11643 % | DWS Investments UK Limited | 2,059,713 | 2,028,702 | 31.12.2023 |
12.96794 % | Fidelity Management & Research Company LLC | 12,620,404 | 448,359 | 31.12.2023 |
11.15271 % | Polaris Venture Partners | 10,853,817 | -1,000,000 | 31.12.2023 |
1.63177 % | JP Morgan Asset Management | 1,588,041 | -421,374 | 31.12.2023 |
1.46984 % | BlackRock Financial Management, Inc. | 1,430,446 | 10,792 | 31.12.2023 |
1.41984 % | Geode Capital Management, L.L.C. | 1,381,786 | 78,709 | 31.12.2023 |
1.34387 % | Euclidean Capital, L.L.C. | 1,307,858 | 0 | 31.12.2023 |
1.18143 % | T. Rowe Price Associates, Inc. | 1,149,770 | 54,313 | 31.12.2023 |
1.09722 % | Deerfield Management Company, L.P. | 1,067,810 | 12,618 | 31.12.2023 |
0.98392 % | Franklin Advisers, Inc. | 957,551 | 33 | 31.12.2023 |
0.86142 % | Jacobs Levy Equity Management, Inc. | 838,331 | 14,858 | 31.12.2023 |
0.78544 % | Dimensional Fund Advisors, L.P. | 764,394 | 83,169 | 31.12.2023 |
0.78513 % | FundLogic SAS | 764,089 | 376,314 | 31.12.2023 |
0.73910 % | King (Robert Siang-Shu) | 719,296 | 169,669 | 31.3.2023 |
0.62670 % | Dafna Capital Management, LLC | 609,905 | -19,033 | 31.12.2023 |
0.60177 % | Two Sigma Investments, LP | 585,647 | 94,216 | 31.12.2023 |
0.58773 % | Renaissance Technologies LLC | 571,983 | 69,780 | 31.12.2023 |
0.57993 % | Morgan Stanley Investment Management Inc. (US) | 564,386 | 28,281 | 31.12.2023 |
0.56945 % | Northern Trust Investments, Inc. | 554,186 | 10,875 | 31.12.2023 |
0.51329 % | Charles Schwab Investment Management, Inc. | 499,529 | 17,307 | 31.12.2023 |
0.50584 % | AllianceBernstein L.P. | 492,285 | 162,664 | 31.12.2023 |
0.45244 % | BofA Global Research (US) | 440,315 | 15,702 | 31.12.2023 |
0.44314 % | Nuveen LLC | 431,266 | -280 | 31.12.2023 |
0.39955 % | BlackRock Advisors (UK) Limited | 388,846 | -1,202 | 31.3.2024 |
0.36546 % | BlackRock Asset Management Ireland Limited | 355,666 | 9,913 | 31.12.2023 |
0.35545 % | Baillie Gifford & Co. | 345,924 | -22,048 | 31.12.2023 |
0.34892 % | New Leaf Venture Partners LLC | 339,569 | 0 | 31.12.2023 |
0.26934 % | Walleye Capital LLC | 262,126 | 262,126 | 31.12.2023 |
0.25758 % | BlackRock Investment Management (UK) Ltd. | 250,681 | -6,754 | 31.12.2023 |
0.24950 % | Goldman Sachs & Company, Inc. | 242,811 | 75,808 | 31.12.2023 |
0.24725 % | Campbell & Company, Inc. | 240,625 | 240,625 | 31.12.2023 |
0.24570 % | HRT Financial LP | 239,116 | 45,822 | 31.12.2023 |
0.24316 % | PanAgora Asset Management Inc. | 236,645 | -56,889 | 31.12.2023 |
0.24212 % | Millennium Management LLC | 235,635 | -121,130 | 31.12.2023 |
0.23861 % | Jupiter Asset Management Ltd. | 232,219 | 0 | 31.12.2023 |
0.19855 % | Barclays Bank PLC | 193,228 | 60,927 | 31.12.2023 |
0.19805 % | Medici Capital LLC | 192,747 | 133,093 | 31.12.2023 |
0.19617 % | Rafferty Asset Management LLC | 190,911 | 4,287 | 31.12.2023 |
0.19553 % | Nordea Funds Oy | 190,290 | -12,417 | 31.12.2023 |
0.18922 % | D. E. Shaw & Co., L.P. | 184,147 | 65,129 | 31.12.2023 |
0.18361 % | UBS Financial Services, Inc. | 178,692 | 99,010 | 31.12.2023 |
0.18071 % | Alphabet, Inc. | 175,866 | 0 | 31.12.2023 |
0.18071 % | JPMorgan Asset Management U.K. Limited | 175,863 | -17,371 | 31.12.2023 |
0.17886 % | BlackRock Investment Management, LLC | 174,069 | 9 | 31.12.2023 |
0.17645 % | Point72 Asset Management, L.P. | 171,726 | -567,056 | 31.12.2023 |
0.17123 % | BNY Mellon Asset Management | 166,642 | -22,878 | 31.12.2023 |
0.16731 % | Cubist Systematic Strategies, LLC | 162,829 | 153,212 | 31.12.2023 |
0.15885 % | Alphacrest Capital Management LLC | 154,590 | 144,190 | 30.9.2022 |
0.15089 % | Kenkare-Mitra (Saraswati) | 146,844 | -10,169 | 4.3.2024 |
0.15066 % | Baillie Gifford Overseas Ltd. | 146,621 | 0 | 29.2.2024 |
0.15048 % | Verition Fund Management LLC | 146,445 | -20,559 | 31.12.2023 |
0.14977 % | Stifel, Nicolaus & Company, Incorporated | 145,759 | 119,609 | 31.12.2023 |
0.14664 % | Acadian Asset Management LLC | 142,711 | -10,555 | 31.12.2023 |
0.13259 % | State of Wisconsin Investment Board | 129,033 | -18,711 | 31.12.2023 |
0.12885 % | Victory Capital Management Inc. | 125,392 | -9,326 | 31.12.2023 |
0.12731 % | Schweizerische Nationalbank | 123,900 | -11,700 | 31.12.2023 |
0.12124 % | Manulife Investment Management (North America) Limited | 117,994 | 39,783 | 31.12.2023 |
0.11532 % | Grasso (Marc) | 112,230 | -5,716 | 4.3.2024 |
0.11482 % | TD Asset Management Inc. | 111,738 | -7,400 | 31.12.2023 |
0.11395 % | Romano (Gary) | 110,893 | -6,001 | 4.3.2024 |
0.11039 % | Columbia Threadneedle Investments (US) | 107,431 | 27,357 | 31.12.2023 |
0.10910 % | Nordea Investment Management AB (Denmark) | 106,179 | 0 | 29.2.2024 |
0.10833 % | Jane Street Capital, L.L.C. | 105,425 | 43,362 | 31.12.2023 |
0.10588 % | Conestoga Capital Advisors, LLC | 103,038 | -2,839 | 29.2.2024 |
0.10520 % | EntrepreneurShares LLC | 102,381 | 50,916 | 31.12.2023 |
0.10285 % | JPMorgan Private Bank (United States) | 100,094 | 14,374 | 31.12.2023 |
0.10275 % | Deka Vermögensmanagement GmbH | 100,000 | 0 | 31.12.2023 |
0.09757 % | BNP Paribas Securities Corp. North America | 94,955 | 14,287 | 31.12.2023 |
0.09001 % | Rhumbline Advisers Ltd. Partnership | 87,598 | -83 | 31.12.2023 |
0.08765 % | Credit Suisse Funds AG | 85,298 | 2,911 | 31.12.2023 |
0.08482 % | Citi Investment Research (US) | 82,544 | 3,021 | 31.12.2023 |
0.08139 % | Susquehanna International Group, LLP | 79,205 | -3,965 | 31.12.2023 |
0.07522 % | State Teachers Retirement System of Ohio | 73,200 | 0 | 31.12.2023 |
0.07458 % | American Century Investment Management, Inc. | 72,583 | -3,086 | 31.12.2023 |
0.07282 % | Wehner (David M) | 70,871 | 26,250 | 14.6.2023 |
0.06967 % | Virginia Retirement System | 67,800 | -4,000 | 30.9.2023 |
0.06825 % | California State Teachers Retirement System | 66,424 | -2,833 | 31.12.2023 |
0.06800 % | Cannell & Co. | 66,177 | -22,075 | 31.12.2023 |
0.06748 % | AQR Capital Management, LLC | 65,667 | 1,870 | 31.12.2023 |
0.06728 % | XTX Markets LLC | 65,478 | 28,312 | 31.12.2023 |
0.06653 % | Assenagon Asset Management S.A. | 64,744 | 4,702 | 29.2.2024 |
0.06421 % | Morgan Stanley Smith Barney LLC | 62,491 | -1,908 | 31.12.2023 |
0.06293 % | Mirae Asset Global Investments (USA) LLC | 61,239 | 2,120 | 31.12.2023 |
0.06251 % | BlackRock Asset Management Canada Limited | 60,835 | 14,365 | 31.12.2023 |
0.06167 % | Federated MDTA LLC | 60,016 | -50,903 | 31.12.2023 |
0.06148 % | IndexIQ Advisors LLC | 59,829 | 59,829 | 31.3.2024 |
0.06128 % | Legal & General Investment Management Ltd. | 59,642 | -169 | 31.12.2023 |
0.06037 % | Los Angeles Capital Management LLC | 58,756 | 0 | 31.3.2024 |
0.06030 % | Flint Jonathan A | 58,686 | 58,686 | 31.12.2023 |
0.05897 % | Northern Trust Global Investments | 57,393 | -13,193 | 31.12.2023 |
0.05835 % | Alps Advisors, Inc. | 56,790 | -5,042 | 31.12.2023 |
0.05320 % | T. Rowe Price International Ltd | 51,779 | 269 | 31.12.2023 |